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Structure of the toxic core of alpha-synuclein from invisible crystals

Rodriguez JA, Ivanova MI, Sawaya MR, Cascio D, Reyes FE, Shi D, Sangwan S, Guenther EL, Johnson LM, Zhang M, Jiang L, Arbing MA, Nannenga BL, Hattne J, Whitelegge J, Brewster AS, Messerschmidt M, Boutet S, Sauter NK, Gonen T, Eisenberg DS

NATURE 525 486-490 (2015) PMID: 26352473

EMDB › EMD-3001

http://www.ebi.ac.uk/pdbe/entry/emdb/EMD-3001/

Electron crystallography

1.4Å resolution

MicroED structure of the segment, GVVHGVTTVA, from the A53T familial mutant of Parkinson’s disease protein, alpha-synuclein, residues 47-56

Map released: 2015-09-09

Last modified: 2015-10-07

Overview of EMD-3001

Source organism: Homo sapiens [9606]

Fitted atomic model: 4znn

Related EM entry by publication: EMD-3028

Primary publication:

Structure of the toxic core of alpha-synuclein from invisible crystals

Rodriguez JA, Ivanova MI, Sawaya MR, Cascio D, Reyes FE, Shi D, Sangwan S, Guenther EL, Johnson LM, Zhang M, Jiang L, Arbing MA, Nannenga BL, Hattne J, Whitelegge J, Brewster AS, Messerschmidt M, Boutet S, Sauter NK, Gonen T, Eisenberg DS

NATURE 525 486-490 (2015) PMID: 26352473