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Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexes.

Arnett, K.L., Hass, M., McArthur, D.G., Ilagan, M.X., Aster, J.C., Kopan, R., Blacklow, S.C.

Nat.Struct.Mol.Biol. 17: 1312-1317 (2010)

PDB ID: 3NBN

http://www.rcsb.org/pdb/explore.do?structureId=3NBN

Crystal structure of a dimer of Notch Transcription Complex trimers on HES1 DNA

DOI: 10.2210/pdb3nbn/pdb

Classification: TRANSCRIPTION / DNA

Deposited: 2010-06-03 Released: 2010-11-03

Deposition author(s): Arnett, K.L., Blacklow, S.C.

Organism: Homo sapiens

Expression System: Escherichia coli, Escherichia coli, Escherichia coli

Structural Biology Knowledgebase: 3NBN (6 models >16 annotations) SBKB.org

Experimental Data Snapshot

Method: X-RAY DIFFRACTION

Resolution: 3.45 Å

R-Value Free: 0.298

R-Value Work: 0.254

wwPDB Validation Full Report

Primary Citation

Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexes.

Arnett, K.L., Hass, M., McArthur, D.G., Ilagan, M.X., Aster, J.C., Kopan, R., Blacklow, S.C.

Nat.Struct.Mol.Biol. 17: 1312-1317 (2010)

PubMed: 20972443 Search on PubMed